Synastol®TC (Terminalia Chebula Fruit Extract):
What it is:
A standardized extract of Terminalia chebula, a broad-spectrum antioxidant known for its high ORAC activity. We formulate with a standardised grade (Synastol® TC) to keep composition consistent.
What the research says:
In clinical studies on the ingredient, Synastol® TC improved the appearance of fine lines, uneven tone and the under-eye area over 4–12 weeks. In-vitro tests showed reductions in reactive oxygen species (ROS) and lipid peroxidation induced by sun, pollution and blue light, and lowered pro-inflammatory markers IL-6/IL-8.
What this means for you:
Within a circadian routine, chebula helps bolster daytime defence against everyday stressors and supports night-time recovery, so toe can look more even, skin feels calmer, and radiance looks steadier over time. Chebula is not a sunscreen; always pair with SPF by day.
Found in: Replenish – Plumping and Radiance Serum (Day/Night)
Hyalo-Oligo® (Hydrolyzed Hyaluronic Acid)
What it is:
An extra-low molecular weight hyaluronic acid (avg. <10 kDa) engineered to penetrate the stratum corneum (horny layer) and bind water, rather than sitting only on the surface. We formulate with the Hyalo-Oligo® grade for consistency and purity.
What the research says:
Supplier studies on the ingredient report detectable penetration into the stratum corneum and long-lasting moisturisation, assessed by skin conductance, that can persist after washing and beyond 24–48 hours in test conditions. In-vitro/clinical materials also note reduced water loss signals vs. conventional HAs of higher molecular weight.
What this means for you:
In Replenish, Hyalo-Oligo® delivers fast, water-binding hydration into the outer skin layer for a supple, dewy, plump-looking finish that layers beautifully under oils and SPF – day and night.
Found in: Replenish – Plumping and Radiance Serum (Day/Night)
Synoxyl® AZ (Acetyl Zingerone)
What it is:
A multi-target antioxidant molecule (acetyl zingerone) inspired by the ginger metabolite zingerone. Formulated for microbiome-friendly, 24/7 support against the visible effects of environmental and photo-induced stress. We formulate with the Synoxyl® AZ grade for consistency and stability.
What the research says:
In clinical studies on the ingredient, Synoxyl® AZ delivered >25% reductions in wrinkle severity/volume and pigment intensity in 4 weeks vs placebo. It also maintained microbiome diversity (including a >20% increase in Staph. epidermidis) and reduced UV-challenge redness by ~40% in study conditions.
What this means for you:
In your morning ritual, Synoxyl® AZ helps support daytime defence and post-exposure calm and recovery, so skin can look smoother, more even, and less reactive-looking over time. AZ is not a sunscreen; always pair with SPF.
Found in: Shield – Broad-Action Antioxidant Face Oil (Day)
HydraSynol® DOI (Isosorbide Dicaprylate)
What it is:
A lipophilic “smart” skin hydrator and barrier builder that helps redistribute moisture where it’s needed. We formulate with the HydraSynol® DOI grade for consistency and stability.
What the research says:
In clinical studies on the ingredient, HydraSynol® DOI provided long-lasting hydration (reported >48 hours) and helped maintain hydration even after a regression period. In vitro data indicate up-regulation of markers linked to barrier function (e.g., Aquaporin-3, tight-junction and desmosomal proteins), supporting improved water movement and cohesion in the outer skin layers.
What this means for you:
Within a circadian routine, HydraSynol® DOI helps skin feel cushioned and comfortable throughout the day and supports overnight moisture resilience. Use under SPF by day (in Shield) to keep dryness and “tight” feel at bay and leave skin looking supple and well-nourished.
Found in: Shield – Broad-Action Antioxidant Face Oil (Day)
